Diagnosis of Myositis

Creatine kinase is the most specific blood test -  5-50 times above the reference level.     A level greater than 100 times the reference level is rare and is a signal of other diagnoses.

Muscle biopsy - Medscape Reference


Erythrocyte sedimentation rate (esr) often elevated.

Myoglobinuria may be present.

Positive rheumatoid factor in more than 50% of patients.

Positive antinuclear antibody results in less than 50% of patients.

Leukocytosis is present in more than 50% of patients



Diagnostic Criteria for Polymyositis/Dermatomyositis at The Myositis Association
Diagnostic Criteria for Inclusion Body Myositis at The Myositis Association
Diagnostic Criteria for Juvenile Dermatomyositis at The Myositis Association



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