INCLUSION BODY MYOSITIS
What is Inclusion Body Myositis?
Inclusion body myositis (IBM) is one of a group of muscle diseases known as the inflammatory myopathies, which are characterized by chronic, progressive muscle inflammation accompanied by muscle weakness. The onset of muscle weakness in IBM is generally gradual (over months or years) and affects both proximal (close to the trunk of the body) and distal (further away from the trunk) muscles. Muscle weakness may affect only one side of the body. Falling and tripping are usually the first noticeable symptoms of IBM. For some individuals, the disorder begins with weakness in the wrists and fingers that causes difficulty with pinching, buttoning, and gripping objects. There may be weakness of the wrist and finger muscles and atrophy (thinning or loss of muscle bulk) of the forearm muscles and quadricep muscles in the legs. Difficulty swallowing occurs in approximately half of IBM cases. Symptoms of the disease usually begin after the age of 50, although the disease can occur earlier. IBM occurs more frequently in men than in women.
Is there any treatment?
What is the prognosis?
IBM is generally resistant to all therapies and its rate of progression appears to be unaffected by currently available treatments.
What research is being done?
NIH Patient Recruitment for Inclusion Body Myositis Clinical Trials
- At NIH Clinical Center
- Throughout the U.S. and Worldwide
- NINDS Clinical Research Collaboration Trials
Myositis Association 1737 King Street Suite 600 Alexandria, VA 22314 tma@myositis.org http://www.myositis.org Tel: 703-299-4850 800-821-7356 Fax: 202-466-8940 |
American Autoimmune Related Diseases Association 22100 Gratiot Avenue Est Detroit, MI 48021-2227 aarda@aarda.org http://www.aarda.org Tel: 586-776-3900 800-598-4668 Fax: 586-776-3903 |
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Myositis Outcomes Workshop
Health Disparities Working Group Meeting: Cognitive and Emotional Health Myositis Outcomes Workshop - Inflammatory Myopathies Fact Sheet
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National Institute of Neurological Disorders and Stroke
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NINDS health-related material is provided for information purposes only and does not necessarily represent endorsement by or an official position of the National Institute of Neurological Disorders and Stroke or any other Federal agency. Advice on the treatment or care of an individual patient should be obtained through consultation with a physician who has examined that patient or is familiar with that patient's medical history.
Inclusion Body Myositis from Medscape Reference - quite technical
Inclusion body myositis (IBM) from Muscular Dystrophy Campaign
INCLUSION BODY MYOSITIS a good, slightly technical, pdf overview on IBM both sporadic and hereditary types by Bill Tillier
INCLUSION BODY MYOSITIS a site by Bill Tillier
Course and therapy of inclusion body myositis from UpToDate
Novel Therapeutic Approaches : Is Inclusion Body Myositis a Primary Degenerative Disease? from Medscape News - quite technical
Treatment & Management from Medscape Reference
Inclusion Body Myopathy 2 Distal Myopathy with Rimmed Vacuoles (DMRV), IBM2 from National Center for Biotechnology Information, U.S. National Library of Medicine
Sporadic inclusion body myositis from Orphanet
Inclusion Body Myositis – Treatment and Symptom Management PDF
The current status of treatment for inclusion-body myositis PDF
Treatment Information, Diagnosis and Symptoms from John Hopkins Medicine
Inclusion Body Myositis Treatments in Alternative Medicine